Mechanisms of ATF4-mediated neuronal apoptosis
نویسندگان
چکیده
.............................................................................................................................. ii Co-Authorship Statement................................................................................................... iv Acknowledgments............................................................................................................... v Table of
منابع مشابه
Molecular pathways of protein synthesis inhibition during brain reperfusion: implications for neuronal survival or death.
Protein synthesis inhibition occurs in neurons immediately on reperfusion after ischemia and involves at least alterations in eukaryotic initiation factors 2 (eIF2) and 4 (eIF4). Phosphorylation of the alpha subunit of eIF2 [eIF2(alphaP)] by the endoplasmic reticulum transmembrane eIF2alpha kinase PERK occurs immediately on reperfusion and inhibits translation initiation. PERK activation, along...
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